5-Methoxy-N,N-dimethyl-1H-indole-3-methanamine → 5-methoxy-3-methyl-1H-indole

Beteiligte Stoffe

Reaktionsschritte

A solution of 5-methoxygramine (3.96 g) in absolute ethanol (80 ml) with 10% Palladium on carbon (0.40 g) is hydrogenated at atmospheric pressure for 10 hours. The catalyst is removed by vacuum filtration through Hy-Flo and the filtrate is concentrated in vacuo to give an oil which crystallizes on standing to give 5-methoxy-3-methylindole.

Herkunft & Nachweise