Hydrochloric Acid → HCID 54712695, Verbindung

Reaktionsgleichung

[O:1]=[C:2]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=[C:3]1[NH:9][C:10]([C:12]1[N:13]([CH3:35])[S:14](=[O:34])(=[O:33])[C:15]2[CH:32]=[CH:31][CH:30]=[CH:29][C:16]=2[C:17]=1[O:18]C(=O)C=CC1C=CC=CC=1)=[O:11].[OH-].[Na+].Cl>CO>[OH:18][C:17]1[C:16]2[CH:29]=[CH:30][CH:31]=[CH:32][C:15]=2[S:14](=[O:33])(=[O:34])[N:13]([CH3:35])[C:12]=1[C:10]([NH:9][C:3]1[C:2](=[O:1])[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1)=[O:11]

Komponenten

Versuchsvorschrift

To a suspension of N-(1-oxo-2,4,6-cycloheptatrien-2-yl)-2-methyl-4-cinnamoyloxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide (0.5 g) in methanol (50 ml) was added dropwise 1N sodium hydroxide solution (1.5 ml) at room temperature. The mixture was stirred for 8 hours at room temperature and then neutralized with 1N hydrochloric acid. The mixture was evaporated under reduced pressure and the residue was washed with water and dried to give crystals, which were recrystallized from N,N-dimethylformamide to give 4-hydroxy-2-methyl-N-(1-oxo-2,4,6-cycloheptatrien-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide (0.1 g).