Fumarate → bromomesaconic acid

HRID 1719789Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1719789
[Br:1][CH2:2]/[C:3](=[CH:7]/[C:8]([OH:10])=[O:9])/[C:4]([OH:6])=[O:5].C([O-])(=O)/C=C/C([O-])=O.BrCC1C(OC(=O)C=1)=O>>[Br:1][CH2:2]/[C:3](=[CH:7]\[C:8]([OH:10])=[O:9])/[C:4]([OH:6])=[O:5]

Komponenten

4

Edukt 3

HCID 5460307FumarateHCID 109870762,5-Furandione, 3-(bromomethyl)-HCID 86740308HCID 86740308, Verbindung2×

Produkt 1

HCID 6449799bromomesaconic acid

Versuchsvorschrift

Steps are taken to avoid isomerization of 2-(bromomethyl)-maleic acid (3) to the corresponding fumarate analog by hydrolyzing the anhydride (2) in a dilute aqueous solution and neutralizing the diacid (3) immediately after complete hydrolysis. Any bromomethyl fumaric acid derivative formed is removed in purifying compound (4) as described in more detail below.

Aufarbeitung

  1. customimmediately after complete hydrolysis

Quellen und Nachweise

ORD-Eintrag
ord-43639ec7cebd449e9e16cfeaedc3e4fd
Quelldatensatz
uspto-grants-1985_09
Patentnummer
US04542225

Notizen zur Reaktion

Wird geladen…