Piperazine → HCID 19429145, Verbindung
Reaktionsgleichung
[CH3:1][C:2]([CH3:18])([CH3:17])[CH2:3][NH:4][C:5]1[N:10]=[C:9](Cl)[CH:8]=[C:7]([N:12]2[CH2:16][CH2:15][CH2:14][CH2:13]2)[N:6]=1.[NH:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1>>[CH3:1][C:2]([CH3:18])([CH3:17])[CH2:3][NH:4][C:5]1[N:10]=[C:9]([N:19]2[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]2)[CH:8]=[C:7]([N:12]2[CH2:16][CH2:15][CH2:14][CH2:13]2)[N:6]=1Komponenten
3
Versuchsvorschrift
The reaction of 2-(2,2-dimethylpropylamino)-4-chloro-6-pyrrolidinopyrimidine with piperazine as described in Example 17 leads to the title compound in a yield of 76%, m.p.: 118°-120° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-d89bcb59e4504ce89722d3e2d9598907
- Quelldatensatz
- uspto-grants-1996_04
- Patentnummer
- US05510345
Notizen zur Reaktion
Wird geladen…