HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethyl Acetate → 1-(4-Aminophenyl)-3-n-butyl-3-azabicyclo[3.1.1]heptane-2,4-dione
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethyl Acetate | HCID 8857 | — |
| Edukt | 3-n-Butyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.1]heptane-2,4-dione | HCID 20027825 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 1-(4-Aminophenyl)-3-n-butyl-3-azabicyclo[3.1.1]heptane-2,4-dione | HCID 20027835 | — |
Reaktionsschritte
In a manner analogous to that described in Example 1, 2.08 g of 3-n-butyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.1]heptane-2,4-dione in 60 ml of ethanol are hydrogenated in the presence of 0.15 g of palladium-on-carbon and worked up. Melting point 178°-179° (from ethyl acetate).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04857660 |
| Quelldatensatz | uspto-grants-1989_08 |
| ORD ID | ord-0480180e286a4a32ab5281af83f17dc8 |
| Quellennotiz | uspto-grants-1989_08 |