[Cl:1][C:2]1[C:7]([O:8][CH:9]([CH3:11])[CH3:10])=[CH:6][C:5]([N:12]2[C:17](=[O:18])[C:16]3[CH2:19][CH2:20][CH2:21][C:15]=3[NH:14][C:13]2=[O:22])=[C:4]([F:23])[CH:3]=1.[CH3:24]I>C[O-].[Na+].CO>[Cl:1][C:2]1[C:7]([O:8][CH:9]([CH3:11])[CH3:10])=[CH:6][C:5]([N:12]2[C:17](=[O:18])[C:16]3[CH2:19][CH2:20][CH2:21][C:15]=3[N:14]([CH3:24])[C:13]2=[O:22])=[C:4]([F:23])[CH:3]=1using 3-(4-chloro-2-fluoro-5-isopropoxyphenyl)-1,5,6,7-tetrahydro-2H-cyclopenta[d]pyrimidine-2,4(3H)dione in sodium methylate/methanol with methyl iodide there is obtained 3-(4-chloro-2-fluoro-5-isopropoxyphenyl)-1,5,6,7-tetrahydro-1-methyl-2H-cyclopenta[d]-pyrimidine-2,4(3H)-dione, m.p. 125°-127° C.;
Wird geladen…