HCID 19014057, Verbindung → HCID 19014054, Verbindung
Reaktionsgleichung
C([CH:5]([C:17]([OH:19])=[O:18])[O:6][C:7]1[CH:8]=[C:9]([CH2:13][C:14](=[O:16])[CH3:15])[CH:10]=[CH:11][CH:12]=1)(C)(C)C>FC(F)(F)C(O)=O>[C:17]([CH2:5][O:6][C:7]1[CH:8]=[C:9]([CH2:13][C:14](=[O:16])[CH3:15])[CH:10]=[CH:11][CH:12]=1)([OH:19])=[O:18]Komponenten
3
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To m-(t-butylcarboxymethoxy)phenyl acetone, 6.7 g, was added trifluoroacetic acid (40 ml) at room temperature under nitrogen. After five minutes, reaction was found to be completed by tlc (silica gel eluted with 1:9 parts by volume methanol:methylene chloride) and the solvent was then evaporated to dryness. The resulting brown oil showed the desired product and trace of starting material on tlc. IR showed characteristic carboxylic acid peak at 3600-2450 cm-1.
Aufarbeitung
- customreaction
- washto be completed by tlc (silica gel eluted with 1:9 parts by volume methanol:methylene chloride)