HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Chloro-6-methoxyquinoline → 4-[3-(1-Acetyl-4-piperidyl)-1-propenyl]-6-methoxyquinoline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Chloro-6-methoxyquinoline | HCID 228348 | — |
| Edukt | HCID 20628273 | HCID 20628273 | — |
| Edukt | Butyllithium | HCID 178418339 | — |
| Katalysator | Methyltriphenyliphosphonium bromide | HCID 74505 | — |
| Produkt | 4-[3-(1-Acetyl-4-piperidyl)-1-propenyl]-6-methoxyquinoline | HCID 292208 | — |
Reaktionsschritte
Following the procedure of Example 3, 4-chloro-6-methoxyquinoline was reacted with the reaction product of methyl triphenylphosphonium bromide and n-butyllithium. This reaction product was then reacted with N-acetyl-4-piperidine-acetaldehyde to produce 4-[3-(1-acetyl-4-piperidyl)-1-propenyl]-6-methoxyquinoline.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US03989691 |
| Quelldatensatz | uspto-grants-1976_11 |
| ORD ID | ord-2ff92e38ff5f4dc69055f54e34cc78ba |
| Quellennotiz | uspto-grants-1976_11 |