Acrylamide → 3-(1,3,4,9b-Tetrahydro-5-methyl-2H-indeno[1,2-c]pyridin-2-yl) propionic acid amide

HRID 1729997Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1729997
[CH3:1][C:2]1[C:3]2[C:8]([CH:9]3[C:14]=1[CH2:13][CH2:12][NH:11][CH2:10]3)=[CH:7][CH:6]=[CH:5][CH:4]=2.[C:15]([NH2:19])(=[O:18])[CH:16]=[CH2:17]>C(O)C>[CH3:1][C:2]1[C:3]2[C:8]([CH:9]3[C:14]=1[CH2:13][CH2:12][N:11]([CH2:17][CH2:16][C:15]([NH2:19])=[O:18])[CH2:10]3)=[CH:7][CH:6]=[CH:5][CH:4]=2

Komponenten

4

Edukt 2

HCID 6579AcrylamideHCID 214987881,3,4,9b-tetrahydro-5-methyl-2H-indeno[1,2-c]pyridine

Produkt 1

HCID 542618023-(1,3,4,9b-Tetrahydro-5-methyl-2H-indeno[1,2-c]pyridin-2-yl) propionic acid amide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture of 18.5 g of 1,3,4,9b-tetrahydro-5-methyl-2H-indeno[1,2-c]pyridine and 7.1 g of acrylamide in 250 cc of ethanol is boiled at reflux for 6 hours. The reaction mixture is evaporated to dryness, and the resulting title compound is recrystallized from ethanol. M.P. 169°-170°.

Aufarbeitung

  1. temperatureat reflux for 6 hours
  2. customThe reaction mixture is evaporated to dryness
  3. customthe resulting title compound is recrystallized from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-728b01fac3b34c7bbc8bf38383c6e929
Quelldatensatz
uspto-grants-1976_11
Patentnummer
US03991066

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