Sodium hydride → 1-Phthalimidopropyl-3-phenyl-5-chloroindazole
Reaktionsgleichung
[C:1]1([C:7]2[C:15]3[C:10](=[CH:11][CH:12]=[C:13]([Cl:16])[CH:14]=3)[NH:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[H-].[Na+].[C:19]1(=[O:33])[N:23]([CH2:24][CH2:25][CH2:26]Cl)[C:22](=[O:28])[C:21]2=[CH:29][CH:30]=[CH:31][CH:32]=[C:20]12>>[C:22]1(=[O:28])[N:23]([CH:24]([C:14]2[C:13]([Cl:16])=[CH:12][CH:11]=[C:10]3[C:15]=2[C:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)=[N:8][NH:9]3)[CH2:25][CH3:26])[C:19](=[O:33])[C:20]2=[CH:32][CH:31]=[CH:30][CH:29]=[C:21]12Komponenten
4
Versuchsvorschrift
By the procedure similar to that described in Example 24, 3-phenyl-5-chloroindazole (9.2 g), sodium hydride 50% pure (2.3 g) and phthalimidopropyl chloride (9.0 g) were treated to obtain 10.4 g of 1-phthalimidopropyl-3-phenyl-5-chloroindazole. Recrystallization from methanol gave a product having a melting point between 121°-122° C.