HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Mercaptoethanesulfonic acid → Mafosfamide Sodium Salt
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Mercaptoethanesulfonic acid | HCID 598 | — |
| Edukt | 4-Hydroxycyclophosphamide | HCID 99735 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | Mafosfamide Sodium Salt | HCID 104746 | — |
Reaktionsschritte
0.8 g (3.0 mmol) of 4-hydroxycyclophosphamide in 3 ml of water were mixed with 420 mg (3.0 mmol) of 2-mercaptoethanesulphonic acid, with ice water cooling. After 1 hour, the mixture was concentrated under high vacuum and was crystallised.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04623742 |
| Quelldatensatz | uspto-grants-1986_11 |
| ORD ID | ord-619ed1eb67204fd4b7bf039408ffcadd |
| Quellennotiz | uspto-grants-1986_11 |