Pentanoic Acid → 5-(1-pentanoyl)amino-3-(1-methylpiperidin-4-yl)-1H-indole

HRID 1738022

Reaktionsgleichung

Reaktionsgleichung von HRID 1738022
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1.[C:18](O)(=[O:23])[CH2:19][CH2:20][CH2:21][CH3:22]>>[C:18]([NH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1)(=[O:23])[CH2:19][CH2:20][CH2:21][CH3:22]

Komponenten

3

Edukt 2

HCID 7991Pentanoic AcidHCID 118312203-(1-Methylpiperidin-4-yl)-1h-indol-5-amine

Produkt 1

HCID 226113965-(1-pentanoyl)amino-3-(1-methylpiperidin-4-yl)-1H-indoleAusbeute 82 %

Versuchsvorschrift

Beginning with 12.0 mg (0.05 mMol) 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole and 10.0 mg (0.10 mMol) pentanoic acid, 12.8 mg (82%) of the title compound were recovered.

Quellen und Nachweise

ORD-Eintrag
ord-14f45dc4f3fa490fa133e9cc0e9e106d
Quelldatensatz
uspto-grants-1999_10
Patentnummer
US05962473

Verknüpfte Notizen

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