Dichlorodimethylsilane → Chlorodimethyl(1,5,6,7-tetrahydro-2-methyl-3-phenyl-s-indacen-1-yl) silane

HRID 1739527Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1739527
[CH3:1][C:2]1[CH2:3][C:4]2[CH:5]=[C:6]3[C:10](=[CH:11][C:12]=2[C:13]=1[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[CH:9]([Li])[CH2:8][CH2:7]3.[Si:21]([CH3:25])([CH3:24])(Cl)[Cl:22]>C1COCC1>[Cl:22][Si:21]([CH3:25])([CH3:24])[CH:3]1[C:4]2[C:12](=[CH:11][C:10]3[CH2:9][CH2:8][CH2:7][C:6]=3[CH:5]=2)[C:13]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[C:2]1[CH3:1]

Komponenten

4

Edukt 2

HCID 6398DichlorodimethylsilaneHCID 178506814HCID 178506814, Verbindung

Produkt 1

HCID 19350461Chlorodimethyl(1,5,6,7-tetrahydro-2-methyl-3-phenyl-s-indacen-1-yl) silaneAusbeute 96,1 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel2×

Reaktionsbedingungen

Temperatur
22.5 °C

Versuchsvorschrift

(6-Methyl-7-phenyl-1,2,3,5-tetrahydro-s-indacenyl) lithium (17.8305 g, 0.07068 moles) 25 in THF (50 mL) was added dropwise to a solution of Me2SiCl2 (21.3694 g, 0.1656 moles) in THF (100 mL) at 0° C. This mixture was then allowed to stir at 20-25° C. 16 hours. After the reaction period the volatiles were removed and the residue extracted and filtered using hexane. The removal of the hexane resulted in the isolation of the desired product as a viscous yellow oil (23.0231 g, 96.1 percent).

Aufarbeitung

  1. custom16 hours
  2. customAfter the reaction period the volatiles
  3. customwere removed
  4. extractionthe residue extracted
  5. filtrationfiltered
  6. customThe removal of the hexane

Quellen und Nachweise

ORD-Eintrag
ord-f036e0dde9af4a9fae6aa8d642f2feff
Quelldatensatz
uspto-grants-1999_10
Patentnummer
US05965756

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