Methyl 3-(hydroxymethyl)-5-iodobenzoate → Methyl 3-formyl-5-iodobenzoate

HRID 1740306Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1740306
[OH:1][CH2:2][C:3]1[CH:4]=[C:5]([I:13])[CH:6]=[C:7]([CH:12]=1)[C:8]([O:10][CH3:11])=[O:9]>C(OCC)(=O)C.[O-2].[O-2].[Mn+4]>[CH:2]([C:3]1[CH:4]=[C:5]([I:13])[CH:6]=[C:7]([CH:12]=1)[C:8]([O:10][CH3:11])=[O:9])=[O:1]

Komponenten

4

Edukt 1

HCID 21837989Methyl 3-(hydroxymethyl)-5-iodobenzoate

Produkt 1

HCID 21838328Methyl 3-formyl-5-iodobenzoateAusbeute 55,8 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418406HCID 178418406, VerbindungKatalysatorHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

The mixture of methyl 5-hydroxymethyl-3-iodobenzoate (5.0 g) and manganese dioxide (30.0 g) in ethyl acetate (50.0 ml) was heated under reflux for 4 hours. The magnganese dioxide was removed by filtration and the filtrate was evaporated in vacuo to give methyl 5-formyl-3-iodobenzoate (2.77 g).

Aufarbeitung

  1. temperaturewas heated
  2. temperatureunder reflux for 4 hours
  3. customThe magnganese dioxide was removed by filtration
  4. customthe filtrate was evaporated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-8198add690444a2cb28721a0145655f5
Quelldatensatz
uspto-grants-1999_10
Patentnummer
US05968985

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