Phosphorus tribromide → 1-(Bromomethyl)-4-methoxycyclohexane

HRID 1740703

Reaktionsgleichung

Reaktionsgleichung von HRID 1740703
[CH3:1][O:2][CH:3]1[CH2:8][CH2:7][CH:6]([CH2:9]O)[CH2:5][CH2:4]1.P(Br)(Br)[Br:12]>C(Cl)(Cl)(Cl)Cl>[Br:12][CH2:9][CH:6]1[CH2:7][CH2:8][CH:3]([O:2][CH3:1])[CH2:4][CH2:5]1

Komponenten

4

Edukt 2

HCID 24614Phosphorus tribromideHCID 18533153(4-Methoxycyclohexyl)methanol

Produkt 1

HCID 217065291-(Bromomethyl)-4-methoxycyclohexane

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 5943Carbon TetrachlorideLösungsmittel

Versuchsvorschrift

4-Methoxycyclohexylmethanol (10.5 g) was dissolved in carbon tetrachloride (45 g) and cooled with ice. Phosphorus tribromide (2.8 ml) was added dropwise to the above solution and stirred at ambient temperature overnight. The carbon tetrachloride layer was decanted and dried over magnesium sulfate. After filtering, the carbon tetrachloride from the filtrate was evaporated to yield pale yellow colored liquid of bromomethyl-4-methoxycyclohexane.

Aufarbeitung

  1. temperaturecooled with ice
  2. customThe carbon tetrachloride layer was decanted
  3. dry with materialdried over magnesium sulfate
  4. filtrationAfter filtering
  5. customthe carbon tetrachloride from the filtrate was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-1090d29d562a414b84259e233b957a84
Quelldatensatz
uspto-grants-1999_10
Patentnummer
US05972552

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