HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Potassium Hydroxide → 2-Amino-4-methyl-6-(4-phenylbutyl)pyridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Potassium Hydroxide | HCID 14797 | — |
| Edukt | Hydroxyamine hydrochloride | HCID 443297 | — |
| Edukt | 4-Methyl-2-(2,5-dimethylpyrrol-1-yl)-6-(4-phenylbutyl)pyridine | HCID 21834420 | — |
| Lösungsmittel | Water ethanol | HCID 19096565 | — |
| Produkt | 2-Amino-4-methyl-6-(4-phenylbutyl)pyridine | HCID 9856182 | — |
Reaktionsschritte
By analogy to Example 56, Step B, 4-methyl-2-(2,5-dimethylpyrrol-1-yl)-6-(4-phenylbutyl)pyridine was treated with 4,6 equivalents of hydroxylamine hydrochloride and 2.8 equivalents of potassium hydroxide in refluxing ethanol/water to yield 2-amino-4-methyl-6-(4-phenylbutyl)pyridine as a yellow oil.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05972975 |
| Quelldatensatz | uspto-grants-1999_10 |
| ORD ID | ord-a45e950eea1f47caaf71ec61abbd3d97 |
| Quellennotiz | uspto-grants-1999_10 |