Hydrochloric Acid → 5H,6H,7H,8H-imidazo[1,2-a]pyridine-7-carboxylic acid hydrochloride

HRID 1742009Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1742009
[N:1]1[CH:2]=[CH:3][N:4]2[CH2:9][CH2:8][CH:7]([C:10]([O:12]CC)=[O:11])[CH2:6][C:5]=12.[ClH:15]>>[N:1]1[CH:2]=[CH:3][N:4]2[CH2:9][CH2:8][CH:7]([C:10]([OH:12])=[O:11])[CH2:6][C:5]=12.[ClH:15]

Komponenten

3

Edukt 2

HCID 313Hydrochloric AcidHCID 10488048Ethyl 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-7-carboxylate

Produkt 1

HCID 194292905H,6H,7H,8H-imidazo[1,2-a]pyridine-7-carboxylic acid hydrochloride

Versuchsvorschrift

A solution of 0.18 g ethyl 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-7-carboxylate in 10 ml of 3N-HCl was heated overnight under reflux, the reaction mixture was concentrated to dryness under reduced pressure, and the residue was dried, thus giving 0.18 g of 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-7-carboxylic acid·hydrochloride.

Aufarbeitung

  1. temperatureunder reflux
  2. concentrationthe reaction mixture was concentrated to dryness under reduced pressure
  3. customthe residue was dried

Quellen und Nachweise

ORD-Eintrag
ord-34cbeb394ddc43a2ba10bd217a71986e
Quelldatensatz
uspto-grants-1994_08
Patentnummer
US05336679

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