2-Chloroaniline → 3-(2-Chloroanilino)-4-(2-hydroxyanilino)-cyclobut-3-ene-1,2-dione

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

To a solution of 3-ethoxy-4-(2-hydroxyanilino)-cyclobut-3-ene-1,2-dione (50 mg, 0.21 mmol) in DMSO (1.5 mL) was added 2-chloroaniline (0.023 mL, 0.21 mmol) and reaction was stirred at 110° C. overnight. Reaction was purified on HPLC (acetonitrile:water) and product was concentrated down. Solid was dried in vacuo. LC-MS (m/z) 315 (M+).

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