(Ethoxy-phenyl-phosphinoyl)-hydroxy-acetic acid ethyl ester → Hydroxy-(hydroxy-phenyl-phosphinoyl)-acetic acid
Reaktionsgleichung
C([O:3][C:4](=[O:18])[CH:5]([P:7]([O:15]CC)([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8])[OH:6])C>Cl>[OH:6][CH:5]([P:7]([OH:15])([C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)=[O:8])[C:4]([OH:18])=[O:3]Komponenten
3
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a solution of (ethoxy-phenyl-phosphinoyl)-hydroxy-acetic acid ethyl ester (382 mg, 1.41 mmol) in 10 mL of 6 M HCl was heated to reflux overnight. The resulting mixture was concentrated to a minimum volume and lyophilized affording a pale yellow solid (274 mg, 90%)
Aufarbeitung
- temperatureto reflux overnight
- concentrationThe resulting mixture was concentrated to a minimum volume
Quellen und Nachweise
- ORD-Eintrag
- ord-61e73113dd2d4b5c8d27f5617ee056ca
- Quelldatensatz
- uspto-grants-2006_03
- Patentnummer
- US07009054B2
Notizen zur Reaktion
Wird geladen…