HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium hydride → 2-(4-Methoxybenzyl)-2-(3,3,3-trifluoropropyl)malononitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium hydride | HCID 24758 | — |
| Edukt | 3-Bromo-1,1,1-trifluoropropane | HCID 2725114 | — |
| Edukt | 2-(4-Methoxybenzyl)malononitrile | HCID 2764141 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 2-(4-Methoxybenzyl)-2-(3,3,3-trifluoropropyl)malononitrile | HCID 22235014 | 27,7% |
Reaktionsschritte
Using 0.39 g of 2-(4-methoxybenzyl)malononitrile, 5 ml of N,N-dimethylformamide, 0.12 g of sodium hydride (60% in oil), and 0.34 g of 1-bromo-3,3,3-trifluoropropane, and according to the process described in the Production Example 1, there was obtained 0.15 g of 2-(4-methoxybenzyl)-2-(3,3,3-trifluoropropyl)malononitrile (the present compound (89)).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07011838B2 |
| Quelldatensatz | uspto-grants-2006_03 |
| ORD ID | ord-4f1d0aa6a168436cbc40ac0b2139b8df |
| Quellennotiz | uspto-grants-2006_03 |