2-Nitropropane → 4-Methyl-4-nitrovaleronitrile

HRID 1744011Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1744011
[C:1](#[N:4])[CH:2]=[CH2:3].[N+:5]([CH:8]([CH3:10])[CH3:9])([O-:7])=[O:6].[OH-].[Na+]>[Cl-].C([N+](C)(C)C)CCCCCCCCCCCCCCC>[CH3:9][C:8]([N+:5]([O-:7])=[O:6])([CH3:10])[CH2:3][CH2:2][C:1]#[N:4]

Komponenten

5

Edukt 3

HCID 3982-NitropropaneHCID 7855AcrylonitrileHCID 14798Sodium Hydroxide

Produkt 1

HCID 38791404-Methyl-4-nitrovaleronitrile

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8154Hexadecyltrimethylammonium chlorideKatalysator

Versuchsvorschrift

(vii-1) Acrylonitrile and 2-nitropropane are reacted in the presence of hexadecyltrimethyl ammonium chloride in an aqueous alkali solvent such as aqueous sodium hydroxide solution and the like. Then, the reaction mixture is extracted to give 4-methyl-4-nitrovaleronitrile (European Journal of Organic Chemistry (1998), (2), 355–357). The obtained 4-methyl-4-nitrovaleronitrile can be isolated and/or purified by a conventional method, such as crystallization, chromatography and the like, but generally, can be used in the next step without isolation and/or purification.

Aufarbeitung

  1. extractionThen, the reaction mixture is extracted

Quellen und Nachweise

ORD-Eintrag
ord-07d62603c1ef42939130f0e4eab6b31b
Quelldatensatz
uspto-grants-2006_03
Patentnummer
US07012152B2

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