Zurück
HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1744632Erstellt: 25. Oktober 2026

1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride → 1-(4-Chlorophenyl)-N-[2-cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-5-methylpyrazole-4-carboxamide

https://huagongshe.com/reaction/1744632

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chlorideHCID 2776128—
Edukt2-Amino-5-(4-morpholinopiperidin-1-yl)benzonitrileHCID 22227997—
Produkt1-(4-Chlorophenyl)-N-[2-cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-5-methylpyrazole-4-carboxamideHCID 2222810018,3%

Reaktionsschritte

By the reaction and treatment in the same manner as in Example 150 using 1-(4-chlorophenyl)-5-methylpyrazole-4-carboxylic chloride (0.81 g) and 2-amino-5-(4-morpholinopiperidin-1-yl)benzonitrile (0.9 g), the title compound (0.29 g) was obtained, melting point: 212–213° C.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07015218B1
Quelldatensatzuspto-grants-2006_03
ORD IDord-353198af9f28463a99d3471a04a1684d
Quellennotizuspto-grants-2006_03