5-bromo-2-(tetrahydro-2H-pyran-4-yl)pyridine → HCID 86692461, Verbindung
Reaktionsgleichung
Br[C:2]1[CH:3]=[CH:4][C:5]([C:8]2([C:18]#[N:19])[CH2:17][CH2:16][C:11]3([O:15][CH2:14][CH2:13][O:12]3)[CH2:10][CH2:9]2)=[N:6][CH:7]=1.BrC1C=CC(C2CCOCC2)=[N:25]C=1>>[NH2:25][C:2]1[CH:3]=[CH:4][C:5]([C:8]2([C:18]#[N:19])[CH2:17][CH2:16][C:11]3([O:15][CH2:14][CH2:13][O:12]3)[CH2:10][CH2:9]2)=[N:6][CH:7]=1Komponenten
3
Versuchsvorschrift
In Reference Example 75(4), 8-(5-bromopyridin-2-yl)-1,4-dioxaspiro[4,5]decane-8-carbonitrile described in Reference Example 82 was used in place of 5-bromo-2-(tetrahydro-2H-pyran-4-yl)pyridine, and reacted and treated in a similar manner to give the titled compound.
Aufarbeitung
- customreacted
- additiontreated in a similar manner
Quellen und Nachweise
- ORD-Eintrag
- ord-4b6f1eb6a1bb4cd7bdcd54501eb120d5