Ethanol → (2RS,4R)-2-(2,4-dihydroxyphenyl)thiazolidine-4-carboxylic acid

Beteiligte Stoffe

Reaktionsschritte

In a mixed solvent including ethanol (10 ml) and water (10 ml), a solution including 2,4-dihydroxybenzaldehyde (943 mg, 6.83 mmol), L-cysteine hydrochloride monohydrate (1.0 g, 5.69 mmol), and sodium acetate (495 mg, 6.03 mmol) was stirred at room temperature for 14 hours. The produced precipitate was filtered, and a filter cake was washed with water, and ethyl acetate to obtain the target product that is a solid white (1.316 g, 95.8%).

Herkunft & Nachweise