HCID 76183230, Verbindung → Methyl 4,4-difluoro-3-oxobutanoate
Reaktionsgleichung
[F:1][CH:2]([F:10])[C:3]([OH:9])=[CH:4][C:5]([O:7][CH3:8])=[O:6]>CO>[F:1][CH:2]([F:10])[C:3](=[O:9])[CH2:4][C:5]([O:7][CH3:8])=[O:6]Komponenten
3
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
The procedure of Example 4 was repeated using methanol instead of ethanol. After distillation the methyl ester was obtained as a colorless liquid. According to the 1H NMR data the product was a tautomeric mixture of ca. 60% keto form and ca. 40% enol form (methyl 4,4-difluoro-3-hydroxybut-2-enoate).
Aufarbeitung
- distillationAfter distillation the methyl ester
- customwas obtained as a colorless liquid
Quellen und Nachweise
- ORD-Eintrag
- ord-5ca2312bf468435da2dfd0d085194da8
- Quelldatensatz
- uspto-grants-2015_10
- Patentnummer
- US09156771B2
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