3-(2-Bromoethyl)pyridine hydrobromide → Tert-butyl 4,6-dimethyl-2-(2-(methyl(1-(pyridine-3-ylmethyl)piperidine-4-yl)amino)-2-oxoethoxy)pyrimidine-5-ylcarbamate
Reaktionsgleichung
[CH3:1][C:2]1[C:7]([NH:8][C:9](=[O:15])[O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[C:6]([CH3:16])[N:5]=[C:4]([O:17][CH2:18][C:19]([N:21]([CH3:28])[CH:22]2[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]2)=[O:20])[N:3]=1.Br.BrC[CH2:32][C:33]1[CH:34]=[N:35][CH:36]=[CH:37][CH:38]=1>>[CH3:16][C:6]1[C:7]([NH:8][C:9](=[O:15])[O:10][C:11]([CH3:14])([CH3:12])[CH3:13])=[C:2]([CH3:1])[N:3]=[C:4]([O:17][CH2:18][C:19]([N:21]([CH3:28])[CH:22]2[CH2:23][CH2:24][N:25]([CH2:32][C:33]3[CH:34]=[N:35][CH:36]=[CH:37][CH:38]=3)[CH2:26][CH2:27]2)=[O:20])[N:5]=1Komponenten
3
Edukt 2
Produkt 1
Versuchsvorschrift
The title compound was synthesized from Compound 31 and 3-(bromo ethyl)pyridine hydrobromide in the same manner as in Example 32.
Quellen und Nachweise
- ORD-Eintrag
- ord-6a05f47dd76e4922848be88c53060834