1-benzyl-N-methylpiperidin-4-amine → HCID 59336117, Verbindung

HRID 1749307

Reaktionsgleichung

Reaktionsgleichung von HRID 1749307
[NH2:1][C:2]1[C:3]([CH:18]([CH3:20])[CH3:19])=[N:4][C:5]([O:11][CH2:12][C:13]([O:15]CC)=O)=[N:6][C:7]=1[CH:8]([CH3:10])[CH3:9].[CH2:21]([N:28]1[CH2:33][CH2:32][CH:31]([NH:34][CH3:35])[CH2:30][CH2:29]1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[NH2:1][C:2]1[C:7]([CH:8]([CH3:9])[CH3:10])=[N:6][C:5]([O:11][CH2:12][C:13]([N:34]([CH:31]2[CH2:30][CH2:29][N:28]([CH2:21][C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[CH2:33][CH2:32]2)[CH3:35])=[O:15])=[N:4][C:3]=1[CH:18]([CH3:19])[CH3:20]

Komponenten

3

Edukt 2

HCID 41361281-benzyl-N-methylpiperidin-4-amineHCID 59336100Ethyl 2-(5-amino-4,6-diisopropylpyrimidine-2-yloxy)acetate

Produkt 1

HCID 59336117HCID 59336117, Verbindung

Versuchsvorschrift

As in Example 11, a carboxylic acid derivative was synthesized from Compound 13. Then, the title compound was synthesized from the obtained carboxylic acid derivative and 1-benzyl-N-methylpiperidine-4-amine in the same manner as in Example 49.

Quellen und Nachweise

ORD-Eintrag
ord-573dce321f464f46842a0c257cf7fc8f
Quelldatensatz
uspto-grants-2015_10
Patentnummer
US09156817B2

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