2-[(5-Chloropyridin-3-yl)oxy]acetic acid → 2-(5-chloropyridine-3-yloxy)-N-(1-(cyclopropylmethyl)piperidine-4-yl)-N-methylacetamide hydrochloride

HRID 1749320

Reaktionsgleichung

Reaktionsgleichung von HRID 1749320
[Cl:1][C:2]1[CH:3]=[C:4]([O:8][CH2:9][C:10]([OH:12])=O)[CH:5]=[N:6][CH:7]=1.[CH:13]1([CH2:16][N:17]2[CH2:22][CH2:21][CH:20]([NH:23][CH3:24])[CH2:19][CH2:18]2)[CH2:15][CH2:14]1>>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]([O:8][CH2:9][C:10]([N:23]([CH:20]2[CH2:19][CH2:18][N:17]([CH2:16][CH:13]3[CH2:15][CH2:14]3)[CH2:22][CH2:21]2)[CH3:24])=[O:12])[CH:5]=[N:6][CH:7]=1

Komponenten

3

Edukt 2

HCID 222659742-[(5-Chloropyridin-3-yl)oxy]acetic acidHCID 433149081-(cyclopropylmethyl)-N-methylpiperidine-4-amine

Produkt 1

HCID 684125472-(5-chloropyridine-3-yloxy)-N-(1-(cyclopropylmethyl)piperidine-4-yl)-N-methylacetamide hydrochloride

Versuchsvorschrift

The title compound was synthesized from 2-(5-chloropyridine-3-yloxy)acetic acid and 1-(cyclopropylmethyl)-N-methylpiperidine-4-amine in the same manner as in Example 95.

Quellen und Nachweise

ORD-Eintrag
ord-192d4d45434e48e4bcaf420dc11a2e1c
Quelldatensatz
uspto-grants-2015_10
Patentnummer
US09156817B2

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