2-Morpholinoethylamine → 2-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazole-4-carboxamide

HRID 1750367Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1750367
[C:1]([N:5]1[C:9]([C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)=[C:8]([C:17]2[S:18][CH:19]=[C:20]([C:22]([OH:24])=O)[N:21]=2)[CH:7]=[N:6]1)([CH3:4])([CH3:3])[CH3:2].[O:25]1[CH2:30][CH2:29][N:28]([CH2:31][CH2:32][NH2:33])[CH2:27][CH2:26]1>>[C:1]([N:5]1[C:9]([C:10]2[CH:11]=[CH:12][C:13]([F:16])=[CH:14][CH:15]=2)=[C:8]([C:17]2[S:18][CH:19]=[C:20]([C:22]([NH:33][CH2:32][CH2:31][N:28]3[CH2:29][CH2:30][O:25][CH2:26][CH2:27]3)=[O:24])[N:21]=2)[CH:7]=[N:6]1)([CH3:3])([CH3:4])[CH3:2]

Komponenten

3

Edukt 2

HCID 4082852-MorpholinoethylamineHCID 867212022-(1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazole-4-carboxylic acid

Produkt 1

HCID 867212062-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazole-4-carboxamide

Versuchsvorschrift

Using 2-(1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazole-4-carboxylic acid and 2-morpholinoethanamine and by reaction and purification in the same manner as in the method described in Example 1, step 7, the title compound was obtained.

Aufarbeitung

  1. customby reaction and purification in the same manner as in the method

Quellen und Nachweise

ORD-Eintrag
ord-a2fbec3857814bf48e8f9fe4d9ea8fce
Quelldatensatz
uspto-grants-2015_10
Patentnummer
US09156837B2

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