2-(Pyrimidin-2-yl)benzoic acid → 2-(Pyrimidin-2-yl)-N-[(1S,2S)-2-{[5-(trifluoromethyl)pyrazin-2-yl]amino}cyclopentyl]benzamide
Reaktionsgleichung
CO[C:3]1[CH:27]=[CH:26][C:25](C)=[CH:24][C:4]=1[C:5]([NH:7][C@H:8]1[CH2:12][CH2:11][CH2:10][C@@H:9]1[NH:13][C:14]1[CH:19]=[N:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][N:15]=1)=[O:6].Cl.FC(F)(F)C1N=C[C:35]([NH:38][C@H:39]2[CH2:43][CH2:42]C[C@@H]2N)=[N:36]C=1.N1C=CC=NC=1C1C=CC=CC=1C(O)=O>>[N:38]1[CH:39]=[CH:43][CH:42]=[N:36][C:35]=1[C:3]1[CH:27]=[CH:26][CH:25]=[CH:24][C:4]=1[C:5]([NH:7][C@H:8]1[CH2:12][CH2:11][CH2:10][C@@H:9]1[NH:13][C:14]1[CH:19]=[N:18][C:17]([C:20]([F:21])([F:23])[F:22])=[CH:16][N:15]=1)=[O:6]Komponenten
4
