Toluene → (2S,4S)-benzyl 2-(5-(4'-(2-((2S,4S)-1-((S)-2-(methoxycarbonylamino)-3-methylbutanoyl)-4-(methylthio)pyrrolidin-2-yl)-1H-imidazol-5-yl)biphenyl-4-yl)-1H-imidazol-2-yl)-4-(methoxymethyl)pyrrolidine-1-carboxylate

Reaktionsgleichung

[CH3:1][O:2][C:3]([NH:5][C@@H:6]([CH:57]([CH3:59])[CH3:58])[C:7]([N:9]1[CH2:13][C@@H:12]([S:14][CH3:15])[CH2:11][C@H:10]1[C:16]([NH:18][CH2:19][C:20]([C:22]1[CH:27]=[CH:26][C:25]([C:28]2[CH:33]=[CH:32][C:31]([C:34]3[NH:38][C:37]([C@@H:39]4[CH2:43][C@H:42]([CH2:44][O:45][CH3:46])[CH2:41][N:40]4C(OCC4C=CC=CC=4)=O)=[N:36][CH:35]=3)=[CH:30][CH:29]=2)=[CH:24][CH:23]=1)=O)=O)=[O:8])=[O:4].[C:60]1(C)C=[CH:64][CH:63]=[CH:62][CH:61]=1.C([O-])(=O)C.[NH4+:71].[CH3:72][CH2:73][O:74][C:75](C)=[O:76]>>[CH3:1][O:2][C:3]([NH:5][C@@H:6]([CH:57]([CH3:59])[CH3:58])[C:7]([N:9]1[CH2:13][C@@H:12]([S:14][CH3:15])[CH2:11][C@H:10]1[C:16]1[NH:71][C:20]([C:22]2[CH:23]=[CH:24][C:25]([C:28]3[CH:29]=[CH:30][C:31]([C:34]4[NH:38][C:37]([C@@H:39]5[CH2:43][C@H:42]([CH2:44][O:45][CH3:46])[CH2:41][N:40]5[C:75]([O:74][CH2:73][C:72]5[CH:64]=[CH:63][CH:62]=[CH:61][CH:60]=5)=[O:76])=[N:36][CH:35]=4)=[CH:32][CH:33]=3)=[CH:26][CH:27]=2)=[CH:19][N:18]=1)=[O:8])=[O:4]