Pyridine → HCID 19389470, Verbindung

HRID 1757047Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1757047
[Si:1]([O:8][CH2:9][CH:10]1[O:15][C:14](=[O:16])[CH:13]=[C:12]([OH:17])[CH2:11]1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].N1C=CC=CC=1.[C:24](Cl)(=[O:26])[CH3:25]>ClCCl>[C:24]([O:17][C:12]1[CH2:11][CH:10]([CH2:9][O:8][Si:1]([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2])[O:15][C:14](=[O:16])[CH:13]=1)(=[O:26])[CH3:25]

Komponenten

5

Edukt 3

HCID 1049PyridineHCID 6367Acetyl chlorideHCID 67809616HCID 67809616, Verbindung

Produkt 1

HCID 19389470HCID 19389470, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To 6-t-butyldimethylsilyloxymethyl-5,6-dihydro-4-hydroxy-pyran-2-one (0.26 parts) in dichloromethane (3 cm3) at ambient temperature was added pyridine (0.1 parts) and then acetyl chloride (0.1 parts). After approximately 30 minutes at ambient temperature the reaction mixture was washed with water, dried over MgSO4 and evaporated to yield 4-acetoxy-6-t-butyldimethylsilyloxymethyl-5,6-dihydropyran-2-one (0.2 parts).

Aufarbeitung

  1. washAfter approximately 30 minutes at ambient temperature the reaction mixture was washed with water
  2. dry with materialdried over MgSO4
  3. customevaporated

Quellen und Nachweise

ORD-Eintrag
ord-cc4c16edcc854448b5c8b86d690ffaff
Quelldatensatz
uspto-grants-1995_08
Patentnummer
US05443970

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