HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4,5-Dimethoxy-2-nitrobenzoic acid → 1-(3,4-Dimethoxy-6-nitrobenzoyl)-4-cyclohexylcarbonyl piperidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4,5-Dimethoxy-2-nitrobenzoic acid | HCID 78690 | — |
| Edukt | 4-Cyclohexylcarbonylpiperidine | HCID 5246602 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | 1-(3,4-Dimethoxy-6-nitrobenzoyl)-4-cyclohexylcarbonyl piperidine | HCID 19389218 | — |
Reaktionsschritte
10.3 g of 3,4-dimethoxy-6-nitrobenzoic acid was converted to the corresponding acid chloride as described in Example 43. It was added to a solution containing 8.83 g of 4-cyclohexylcarbonylpiperidine and 4.58 g oftriethylamine in 300 ml of dichloromethane. Yield 16.4 g (90%), m.p. 120°-125° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05446194 |
| Quelldatensatz | uspto-grants-1995_08 |
| ORD ID | ord-4d6bcac3ce234f0b92fc1b2737d21e22 |
| Quellennotiz | uspto-grants-1995_08 |