2-Amino-5-chloropyridine → Benzamide, 2-chloro-N-(((5-chloro-2-pyridinyl)amino)carbonyl)-6-fluoro-

HRID 1758931Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1758931
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([NH2:8])=[N:6][CH:7]=1.[Cl:9][C:10]1[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[C:11]=1[C:12]([NH:14][C:15](Cl)=[O:16])=[O:13]>>[Cl:9][C:10]1[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[C:11]=1[C:12]([NH:14][C:15]([NH:8][C:5]1[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][N:6]=1)=[O:16])=[O:13]

Komponenten

3

Edukt 2

HCID 661742-Amino-5-chloropyridineHCID 537976672-Chloro-6-fluorobenzamidocarboxylic acid chloride

Produkt 1

HCID 174171Benzamide, 2-chloro-N-(((5-chloro-2-pyridinyl)amino)carbonyl)-6-fluoro-

Versuchsvorschrift

A portion of 5-chloro-2-aminopyridine is reacted with 2-chloro-6-fluorobenzamidocarboxylic acid chloride in the presence of a hydrogen halide acceptor as described in Example 12. The product, named in the heading above, is isolated as described in Example 12 to obtain the desired compound, identical to the product of Example 3.

Aufarbeitung

  1. customis isolated

Quellen und Nachweise

ORD-Eintrag
ord-df1e8edb6ce742acb2697cd207d8c47b
Quelldatensatz
uspto-grants-1982_07
Patentnummer
US04338321

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