Benzyl Bromide → HCID 13117017, Verbindung

HRID 1759258Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1759258
[OH:1][C:2]1[CH:3]=[N:4][O:5][CH:6]=1.[CH2:7](Br)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[CH2:7]([O:1][C:2]1[CH:3]=[N:4][O:5][CH:6]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

Komponenten

5

Edukt 3

HCID 7498Benzyl BromideHCID 11430Potassium CarbonateHCID 131170124-hydroxyisoxazole

Produkt 1

HCID 13117017HCID 13117017, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Reaktionsbedingungen

Temperatur
25 °C

Versuchsvorschrift

A mixture containing 200 mg of 4-hydroxyisoxazole in 10 ml of acetone together with 1.5 equivalents of benzyl bromide and 1.5 equivalents of potassium carbonate is stirred at about 25° C. for five hours. The solid is filtered and the filtrate concentrated to an oil. The crude material is purified by chromatography on silica gel.

Aufarbeitung

  1. filtrationThe solid is filtered
  2. concentrationthe filtrate concentrated to an oil
  3. customThe crude material is purified by chromatography on silica gel

Quellen und Nachweise

ORD-Eintrag
ord-8b06d7e984b2497ea462637c04ad794f
Quelldatensatz
uspto-grants-1982_07
Patentnummer
US04339588

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