Thionyl Chloride → 3-Bromo-2,4,5-trifluorobenzoyl chloride

HRID 1761648Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1761648
[Br:1][C:2]1[C:3]([F:13])=[C:4]([CH:8]=[C:9]([F:12])[C:10]=1[F:11])[C:5](O)=[O:6].S(Cl)([Cl:16])=O>>[Br:1][C:2]1[C:3]([F:13])=[C:4]([CH:8]=[C:9]([F:12])[C:10]=1[F:11])[C:5]([Cl:16])=[O:6]

Komponenten

3

Edukt 2

HCID 24386Thionyl ChlorideHCID 27832463-Bromo-2,4,5-trifluorobenzoic acid

Produkt 1

HCID 137488023-Bromo-2,4,5-trifluorobenzoyl chloride

Versuchsvorschrift

A solution of the 3-bromo-2,4,5-trifluorobenzoic acid (2.5 g) in thionyl chloride (10 ml) was refluxed for 2.5 hours, and then concentrated. The resulting residue was purified by distillation through Widmer fractionating column to give the title compound (2.3 g), bp 98°-102° C./18 mmHg.

Aufarbeitung

  1. concentrationconcentrated
  2. distillationThe resulting residue was purified by distillation through Widmer fractionating column

Quellen und Nachweise

ORD-Eintrag
ord-e7c2bcbdd9f2453ebd6e159b46ed4b38
Quelldatensatz
uspto-grants-1989_05
Patentnummer
US04826982

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