Ammonia → HCID 10997097, Verbindung
Reaktionsgleichung
[CH2:1]([N:4]([C:10]([O:12]C)=O)[CH2:5][C:6](OC)=[O:7])[C:2]#[CH:3].[NH3:14]>>[CH2:1]([N:4]1[CH2:5][C:6](=[O:7])[NH:14][C:10]1=[O:12])[C:2]#[CH:3]Komponenten
3
Versuchsvorschrift
3.0 g of methyl N-propargyl-N-methoxycarbonylglycinate were dissolved in 40 ml of 28% aqueous ammonia. Then the mixture was maintained under the pressure of 10-13 kg/cm2 at 100°-110° C. for an hour. Then the solvent was evaporated off from the reaction mixture. The resulting mixture was subjected to a column chromatography on silica gel (5:1 ethyl acetate:methanol as eluent) to obtain 0.65 g of 1-propargyl-2,4-dioxoimidazolidine.
Aufarbeitung
- temperatureThen the mixture was maintained under the pressure of 10-13 kg/cm2 at 100°-110° C. for an hour
- customThen the solvent was evaporated off from the reaction mixture
Quellen und Nachweise
- ORD-Eintrag
- ord-4f522af51f2d43db858a99d16f8429f9
- Quelldatensatz
- uspto-grants-1989_05
- Patentnummer
- US04827020
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