HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1761946Erstellt: 26. Oktober 2026
1-Piperazinecarboxylic acid, ethyl ester → 4-(1,4-Dihydro-3-methyl-1, 4-dioxo-2-naphthalenyl)-1-piperazinecarboxylic acid, ethyl ester
https://huagongshe.com/reaction/1761946
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | 1-Piperazinecarboxylic acid, ethyl ester | HCID 8431 | — |
| Edukt | 2,3-Epoxy-2-methyl-1,4-naphthoquinone | HCID 85845 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 4-(1,4-Dihydro-3-methyl-1, 4-dioxo-2-naphthalenyl)-1-piperazinecarboxylic acid, ethyl ester | HCID 14278765 | 30,5% |
Reaktionsschritte
A mixture of 1.88 g of 2,3-epoxy-3-methyl-1, 4-naphthoquinone, 3.16 g of piperazinecarboxylic acid, ethyl ester and 100 ml of absolute ethanol was stirred for 12 hours at 50° C. The solvent was then removed and the remainder filtered through a one inch plug of silica gel and eluted with chloroform. The eluate was evpaorated, giving 1 g of the desired product as a viscous red oil.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US04829089 |
|---|
| Quelldatensatz | uspto-grants-1989_05 |
|---|
| ORD ID | ord-9b61ae1cede84c45807bb685f57dcfd0 |
|---|
| Quellennotiz | uspto-grants-1989_05 |
|---|
