Hydrochloric Acid → HCID 20043143, Verbindung

HRID 1762291Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1762291
[CH3:1][NH:2][C:3]1[CH2:4][O:5][C:6]2[CH:14]=[CH:13][CH:12]=[CH:11][C:7]=2[C:8](=[O:10])[CH:9]=1.[ClH:15]>CO>[ClH:15].[CH3:1][NH:2][C:3]1[CH2:4][O:5][C:6]2[CH:14]=[CH:13][CH:12]=[CH:11][C:7]=2[C:8](=[O:10])[CH:9]=1

Komponenten

4

Edukt 2

HCID 313Hydrochloric Acid2×HCID 134460473-(Methylamino)-1-benzoxepin-5(2H)-one

Produkt 1

HCID 20043143HCID 20043143, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

19 g 3-methylamino-1-benzoxepin-5(2H)-one were suspended in 130 ml methanol, and gaseous hydrogen chloride was introduced into the suspension with stirring in order to convert it into its hydrochloride. The amine thereby goes into solution with warming. Subsequently approximately 40 ml methanol were distilled from the solution. The solution was allowed to stand to crystallize the hydrochloride which was formed, and the crystals which formed were removed by filtration. 22 g 3-methylamino-1-benzoxepin-5(2H)-one hydrochloride were obtained which were used without further purification in the following hydrogenation.

Aufarbeitung

  1. temperaturewith warming
  2. distillationSubsequently approximately 40 ml methanol were distilled from the solution
  3. customto crystallize the hydrochloride which
  4. customwas formed
  5. customthe crystals which formed
  6. customwere removed by filtration

Quellen und Nachweise

ORD-Eintrag
ord-a205a25a394b419c90fc37aa46f536ef
Quelldatensatz
uspto-grants-1989_05
Patentnummer
US04831167

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