Ammonia → HCID 86743054, Verbindung
Reaktionsgleichung
[ClH:1].[C:2]1([CH2:8][O:9][C:10]([NH:12][CH2:13][CH2:14][C:15]2[C:23]3[C:18](=[CH:19][CH:20]=[C:21]([C:24](=[NH:28])OCC)[CH:22]=3)[NH:17][CH:16]=2)=[O:11])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH3:29]>>[OH2:9].[ClH:1].[NH2:29][N:28]=[CH:24][C:21]1[CH:22]=[C:23]2[C:18](=[CH:19][CH:20]=1)[NH:17][CH:16]=[C:15]2[CH2:14][CH2:13][NH:12][C:10](=[O:11])[O:9][CH2:8][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1Komponenten
3
Versuchsvorschrift
A solution of the product of Stage (i) (0.1 g) in methanolic ammonia solution (25 ml) was stirred at room temperature for 72 h. The mixture was reduced to dryness and the residual oil triturated with a mixture of ethyl acetate and ethanol to give the title compound as a powder (0.06 g), m.p. 248°-250°.
Aufarbeitung
- customthe residual oil triturated with a mixture of ethyl acetate and ethanol
Quellen und Nachweise
- ORD-Eintrag
- ord-ecfba88c16ab46f99d23743a4de4432f
- Quelldatensatz
- uspto-grants-1989_05