HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Bromide ion → 7-(5-Hydroxy-5-methylhexyl)-1,3-dimethylxanthine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Bromide ion | HCID 259 | — |
| Edukt | Methyl iodide | HCID 6328 | — |
| Edukt | Lomifylline | HCID 65599 | — |
| Edukt | 7-(5-Hydroxy-5-methylhexyl)-3-methylxanthine | HCID 13747680 | — |
| Edukt | 1,3-Dimethyl-7-(5-methyl-4-hexenyl)-xanthine | HCID 20041125 | — |
| Edukt | HCID 178418332 | HCID 178418332 | — |
| Lösungsmittel | Diethyl Ether | HCID 3283 | — |
| Produkt | 7-(5-Hydroxy-5-methylhexyl)-1,3-dimethylxanthine | HCID 13747683 | — |
Reaktionsschritte
Alternatively, it was possible to prepare the compound, inter alia, from 7-(5-hydroxy-5-methylhexyl)-3-methylxanthine (Example 1b) and iodomethane analogously to Example 3, from 1,3-dimethyl-7-(5-oxohexyl)-xanthine and methylmagnesium chloride or bromide in anhydrous ether analogously to Example 9, and from 1,3-dimethyl-7-(5-methyl-4-hexenyl)-xanthine by acid-catalyzed hydration analogously to Example 14.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04833146 |
| Quelldatensatz | uspto-grants-1989_05 |
| ORD ID | ord-590b90e31e1c4538baeea3ad2f472939 |
| Quellennotiz | uspto-grants-1989_05 |