Epibromohydrin → HCID 20309580, Verbindung
Reaktionsgleichung
[OH:1][C:2]1[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][C:3]=1[C:4]([CH2:6][CH2:7][C:8]([O:10][CH3:11])=[O:9])=[O:5].[CH2:18]([CH:20]1[O:22][CH2:21]1)Br>>[O:22]1[CH2:21][CH:20]1[CH2:18][O:1][C:2]1[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][C:3]=1[C:4]([CH2:6][CH2:7][C:8]([O:10][CH3:11])=[O:9])=[O:5]Komponenten
3
Versuchsvorschrift
Methyl 3-(2-hydroxy-5-methoxybenzoyl)propionate was reacted with epibromohydrin in a similar manner to that described in Example 1 (ii) to give methyl 3-[2-(2,3-epoxypropoxy)-5-methoxybenzoyl]propionate which, recrystallised from ether-petroleum ether (b.p. 60°-80°), had m.p. 50° - 51.5° C). (Found: C, 60.91; H, 6.07; C15H18O6 requires: C, 61.21; H, 6.17%).
Quellen und Nachweise
- ORD-Eintrag
- ord-4710d8d4b147449ab56e9c0261dbf134
- Quelldatensatz
- uspto-grants-1978_09