HCID 20309894, Verbindung → 2-AMINO-3-CYANO-5-NITROTHIOPHENE

HRID 1763367Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1763367
C([NH:3][C:4]1[S:5][C:6]([N+:12]([O-:14])=[O:13])=[CH:7][C:8]=1[C:9](=O)[NH2:10])=O.C(NC1SC([N+]([O-])=O)=CC=1C(=O)N)(=O)C1C=CC=CC=1>>[NH2:3][C:4]1[S:5][C:6]([N+:12]([O-:14])=[O:13])=[CH:7][C:8]=1[C:9]#[N:10]

Komponenten

3

Edukt 2

HCID 20309894HCID 20309894, VerbindungHCID 20309899HCID 20309899, Verbindung

Produkt 1

HCID 110520602-AMINO-3-CYANO-5-NITROTHIOPHENEAusbeute 60 %

Versuchsvorschrift

In place of the 83.9 parts of 2-formylamino-3-carbamoyl-5-nitrothiophene used in Example 1 there are used 113.6 parts of 2-benzoylamino-3-carbamoyl-5-nitrothiophene, the first stage of the reaction being carried out for 15 minutes at 60° C. (instead of at 70°-75° C. as in Example 1). 2-Amino-3-cyano-5-nitrothiophene is obtained in an overall yield of 60%.

Aufarbeitung

  1. custominstead of at 70°-75° C.

Quellen und Nachweise

ORD-Eintrag
ord-ee346fbc37de48f88dc6746961bf2509
Quelldatensatz
uspto-grants-1978_09
Patentnummer
US04111956

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