Cyclopropanemethanol → (RS)-6-cyclopropylmethoxy-N-(2-hydroxymethyl-butyl)-5-(4-trifluoromethoxy-phenyl)-nicotinamide

Reaktionsgleichung

Br[C:2]1[CH:3]=[C:4]([C:9]([OH:11])=O)[CH:5]=[N:6][C:7]=1Cl.[OH:12][CH2:13][CH:14]1[CH2:16][CH2:15]1.[F:17][C:18]([F:30])([F:29])[O:19][C:20]1[CH:25]=[CH:24][C:23](B(O)O)=[CH:22][CH:21]=1.[NH2:31][CH2:32][CH:33]([CH2:36][CH3:37])[CH2:34][OH:35]>>[CH:14]1([CH2:13][O:12][C:7]2[C:2]([C:23]3[CH:24]=[CH:25][C:20]([O:19][C:18]([F:30])([F:29])[F:17])=[CH:21][CH:22]=3)=[CH:3][C:4]([C:9]([NH:31][CH2:32][CH:33]([CH2:34][OH:35])[CH2:36][CH3:37])=[O:11])=[CH:5][N:6]=2)[CH2:16][CH2:15]1