Cyclopropanemethanol → (RS)-6-cyclopropylmethoxy-N-(2-hydroxymethyl-butyl)-5-(4-trifluoromethyl-phenyl)-nicotinamide

Reaktionsgleichung

Br[C:2]1[CH:3]=[C:4]([C:9]([OH:11])=O)[CH:5]=[N:6][C:7]=1Cl.[OH:12][CH2:13][CH:14]1[CH2:16][CH2:15]1.[F:17][C:18]([F:29])([F:28])[C:19]1[CH:24]=[CH:23][C:22](B(O)O)=[CH:21][CH:20]=1.[NH2:30][CH2:31][CH:32]([CH2:35][CH3:36])[CH2:33][OH:34]>>[CH:14]1([CH2:13][O:12][C:7]2[C:2]([C:22]3[CH:23]=[CH:24][C:19]([C:18]([F:29])([F:28])[F:17])=[CH:20][CH:21]=3)=[CH:3][C:4]([C:9]([NH:30][CH2:31][CH:32]([CH2:33][OH:34])[CH2:35][CH3:36])=[O:11])=[CH:5][N:6]=2)[CH2:16][CH2:15]1