4-Methoxycarbonylphenylboronic acid → HCID 21110891, Verbindung
Reaktionsgleichung
NC1N=CC([C:8]2[CH:16]=[CH:15][C:11]([C:12]([OH:14])=[O:13])=[CH:10][CH:9]=2)=CC=1OCC1C(F)=CC=C(F)C=1Cl.Br[C:29]1[CH:30]=[C:31]([O:36][CH:37]([C:39]2[C:44]([Cl:45])=[CH:43][CH:42]=[CH:41][C:40]=2[Cl:46])[CH3:38])[C:32]([NH2:35])=[N:33][CH:34]=1.COC(C1C=CC(B(O)O)=CC=1)=O>>[NH2:35][C:32]1[N:33]=[CH:34][C:29]([C:8]2[CH:16]=[CH:15][C:11]([C:12]([OH:14])=[O:13])=[CH:10][CH:9]=2)=[CH:30][C:31]=1[O:36][CH:37]([C:39]1[C:44]([Cl:45])=[CH:43][CH:42]=[CH:41][C:40]=1[Cl:46])[CH3:38]Komponenten
4
Versuchsvorschrift
4-{6-Amino-5-[1-(2,6-dichloro-phenyl)-ethoxy]-pyridin-3-yl)-benzoic acid was prepared using the same procedure as 4-[6-amino-5-(2-chloro-3,6-difluoro-benzyloxy)-pyridin-3-yl]-benzoic acid from 5-bromo-3-[1-(2,6-dichloro-phenyl)-ethoxy]-pyridine-2-ylamine and 4-methoxycarbonylbenzeneboronic acid