Acetyl chloride → 2-Acetamidophenylboronic acid
Reaktionsgleichung
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[B:8]([OH:10])[OH:9].C(N(CC)CC)C.[C:18](Cl)(=[O:20])[CH3:19]>>[C:18]([NH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[B:8]([OH:10])[OH:9])(=[O:20])[CH3:19]Komponenten
4
Versuchsvorschrift
A mixture of 2-aminophenylboronic acid (900 mg; 6.6 mmol), triethylamine (0.57 ml; 7 mmol) and acetylchloride (0.5 ml; 7 mmol) was stirred at rt. for 1 h. The reaction mixture was evaporated to dryness, stirred with H2O and filtered to give 750 mg (63%) product.
Aufarbeitung
- customThe reaction mixture was evaporated to dryness
- stirringstirred with H2O
- filtrationfiltered
Quellen und Nachweise
- ORD-Eintrag
- ord-2ace11fd48294c6085ef14e537ac708d
- Quelldatensatz
- uspto-grants-2007_06
- Patentnummer
- US07235548B2
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