Reaktionsgleichung
[F:1][C:2]([F:16])([CH:8]([OH:15])[C:9]1[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=1)[C:3](OCC)=[O:4].[NH2:17][NH2:18]>>[F:1][C:2]([F:16])([CH:8]([OH:15])[C:9]1[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=1)[C:3]([NH:17][NH2:18])=[O:4]Komponenten
3
Versuchsvorschrift
α,α-difluoro-β-hydroxy-3-(4-pyridinyl)-propanoic acid, hydrazide (50) was prepared in the manner described in Example 10 on a 20 mmol scale using ethyl α,α-difluoro-β-hydroxy-3-(4-pyridinyl)-propanoate and hydrazine to yield 2.7 g (62%) of product. This product was used immediately in the manner described in Example 51, below.
Quellen und Nachweise
- ORD-Eintrag
- ord-772d126ea75847e689202feda7164bc5
- Quelldatensatz
- uspto-grants-1995_01
- Patentnummer
- US05378840
Verknüpfte Notizen
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