Potassium Carbonate → 2-(3,4-Dimethoxyphenyl)-4-(2,4,6-trifluorobenzyl)-2H-1,2,4-benzothiadiazin-3(4H)-one 1,1-dioxide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Potassium Carbonate	HCID 11430	—
Edukt	2,4,6-Trifluorobenzyl bromide	HCID 2777059	—
Edukt	2-(4-methoxy-3,5-dimethylphenyl)-4-(2,4,6-trifluorobenzyl)-2H-1,2,4-benzothiadiazin-3(4H)-one 1,1-dioxide	HCID 72722085	—
Lösungsmittel	Dimethylformamide	HCID 6228	—
Produkt	2-(3,4-Dimethoxyphenyl)-4-(2,4,6-trifluorobenzyl)-2H-1,2,4-benzothiadiazin-3(4H)-one 1,1-dioxide	HCID 72721795	—

Reaktionsschritte

The title compound (29 mg, 0.06 mmol) was prepared from (IntA1) (84 mg, 0.25 mmol), K2CO3 (104 mg, 0.75 mmol) and 2,4,6-trifluorobenzyl bromide (68 uL, 0.30 mmol) in DMF (2 mL) using the methods of (115).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US09249160B2
Quelldatensatz	uspto-grants-2016_02
ORD ID	ord-a6b850497dc0481e9819efeb59613c32
Quellennotiz	uspto-grants-2016_02