3-Fluoroaniline → 3-(3-Fluorophenyl)-7-phenylthieno[3,2-d]pyrimidin-4(3H)-one

Beteiligte Stoffe

Reaktionsschritte

In the same manner as the synthesis of Compound 1, methyl 3-amino-4-phenylthiophene-2-carboxylate (50 mg, 0.21 mmol), triethyl orthoformate (0.47 ml), 3-fluoroaniline (44.3 mg, 0.4 mmol), and acetic acid (0.06 ml) were used to give 8.1 mg (0.025 mmol, 12% yield) of the title compound.

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